Drug Development Grant for MND Therapeutics

Donor Name: FightMND

Reference URL:https://fightmnd.org.au/our-work/our-grants/

The Drug Development Grant provide research institutions and investigators with project funding to develop and assess new or repurposed therapeutics for motor neurone disease, advancing promising candidates through preclinical research and, where appropriate, into Phase I clinical trials.

The grants are structured in two development stages, from identifying and validating a lead therapeutic candidate to advancing a candidate supported by strong preclinical evidence towards clinical development. Projects should be product-driven and focused on therapeutics for MND. Proposals may involve new therapeutic development or hypothesis-driven repurposing of compounds already approved for other conditions, with the aim of moving therapies towards human clinical trials.

Stage 1 projects may identify or develop a lead candidate and generate relevant preclinical data. Stage 2 projects should advance a candidate already in hand, generating data needed for clinical development, through to completion of Phase I clinical trials.

Stage 1 grants provide up to AUD$550,000 over three years, and Stage 2 grants provide up to AUD$1,200,000 over three years. More cost-effective proposals that request less than the maximum available are encouraged. Projects are expected to be achievable within three years; shorter projects may also be considered. Continued funding is subject to periodic review, with satisfactory progress reports required every six months.

Applications are invited from research-based institutions in Australia and internationally. Eligible applicants include investigators at all academic levels, pharmaceutical and biotechnology companies, academic institutions and universities, hospitals, and MND researchers. No nationality criteria apply to the primary investigator. Phase I clinical studies must include at least one Australian trial site.

Applications should include relevant preliminary data and a detailed project budget with a year-by-year breakdown. FightMND does not fund institutional indirect costs, overheads, oncosts, capital equipment, depreciation, or equipment maintenance.

For more information, visit FightMND.

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